Elon Musk, the richest person in the world, says he will sell $6 billion worth of Tesla stock and donate the proceeds to the United Nations’ food agency if it could show how the money would solve world hunger.His statement came after U.N. World Food Programme Executive…Musk Offers $6B If UN Shows How it Will Solve World Hunger — Newsmax – Newsfront
A recent story, complete with a picture of dogs being subjected to sand fly bites and inflammatory lies by animal rights groups, is being used to disparage Dr. Anthony Fauci as a heartless, politically motivated scientist. There are a lot of reasons to judge Dr. Fauci harshly, but this is not one of them. Let me explain.
Drug development and testing involves multiple steps to ensure safety and efficacy of a proposed drug before it is given to humans to treat disease. In the case cited in the article from whitecoatwaste.org and echoed by PETA, lies include flies stripping flesh from bones. What is really happening is that anesthetized dogs are being infected with leishmaniasis parasites by bites from infected sand flies in order to test drugs to treat this dreadful tropical disease, which naturally infects dogs, cats, rodents, and humans by millions in tropical-subtropical regions of Africa, Middle East, southern Europe, South and Central America and even the United States. See Leishmaniasis Facts: below for more details about this disease.
The flies are not “stripping the flesh from the bones” as described in the article. Sand fly bites are like mosquito bites, not like being eaten by carrion or blow fly maggots, which this lie implies. After being infected with the parasite through several sand fly bites, the dogs will be treated for the disease by an experimental drug to see how effectively it cures them, and to determine any unpleasant or dangerous side effects of the drug.
Animal testing is a necessary, though disgusting, step in drug development. To ethically carry out this type of procedure, suffering of the animals must be minimized.[1.] That is why the dogs are anesthetized and only their heads are exposed to the sand fly bites. Dogs are the best model for this disease since it naturally infects dogs with a visceral form that can be fatal if untreated. This may be a part of development of veterinary treatment drugs, but it may be used for human drugs as well.
All drugs and cosmetics, as well as many other consumer products, are tested first on cell cultures and then on animals for both safety and effectiveness before graduating to human trials. Covid vaccines and treatment drugs were tested on animals such as genetically modified mice before human trials, but without outrage because there was no cute pet sentimental propaganda.
Animal testing is a necessary step that, though sensibly abhorrent, must be done. Eliminating testing of animal models would mean that drugs, cosmetics or other products would be given to humans without knowing if they might be harmful or be effective for the proposed purpose. Typical animal models used for product development include a variety of vertebrates including dogs, cats, monkeys, Guinea pigs, hamsters, rats and mice. Animal models used to gauge a product’s potential for environmental pollution also include fish, crustaceans like crabs, mollusks like snails, as well as single cell, colony and other microscopic animals.
If a cosmetic or household product advertises that it is not tested on animals, it only means that the ingredients underwent animal tested by others in the past. Re-blending of well-known ingredients may not need more animal testing for each new mixture within reasonable variability.
It is true that animal models are not perfect matches for reactions in humans. Each animal has unique metabolic systems that vary from species to species. What developers try to do is to match human systems as well as possible for the disease and the mechanism of the drug being developed. For instance, some products are affected by whether or not an animal can make its own vitamin C. Humans cannot and have that in common with hamsters, which are sometimes used for toxicology and other testing.
Both White Coat Waste and PETA (People for the Ethical Treatment of Animals) are advocacy groups that are dedicated to ending animal testing of all types. Ending animal testing would end drug, cosmetic and consumer product development. As much as I wish we could end animal testing, this is not possible unless we stop all progress, development or improvement of treatments for still orphaned diseases and conditions.
For example, the progress made by St. Jude in childhood leukemia and cancer treatment is remarkable. At one time, fatality was 80 to 90% for most types. Now, for most of these diseases, fatality is only 20%. This is still too high, but could not have been accomplished without new drug and treatment development. My daughter died over 40 years ago of a type of leukemia that is among those types that still have high fatality. Much research and development is still needed.
Leishmaniasis Facts: Leishmania is caused by a protozoan parasite carried and spread by infected sand flies. Sand flies are tiny, about half the size of mosquitos, and are silent. They are most active dusk to dawn. Only females need blood for egg and parasite development. Sand flies become infected by biting and taking a blood meal from infected dogs, cats, rodents or humans, so a few cases have now been acquired in Texas, probably by sand flies that had bitten immigrants from tropical countries.
Symptoms of visceral leishmania in humans, which may not be evident for months or even years, include fever, weight loss, enlarged spleen and liver, abnormal blood tests with low red and white cells and platelets and may cause kidney failure. The cutaneous form affects skin with nodules and ulcers that develop in a few weeks, but may progress to the visceral form even after the sores heal.
Symptoms in dogs include skin nodules, thickening of foot pads, dull and brittle hair and hair loss patches. Visceral symptoms include fever, loss of appetite, weakness, exercise intolerance, severe weight loss, diarrhea, vomiting, bleeding nose, tarry stools, swollen lymph nodes, enlarged spleen, kidney failure.
Treatment: No one treatment is effective for all cases. It varies with the form and the species/strain of the parasite, and even the geographical location. CDC offers advice for several possible treatments, but does not ensure success for any one of them. Some are not available in developing countries, and some are not available in the United States because the FDA had not approved them. There is a need for development of vaccines and better treatments with a more assured outcome for all strains in all areas.
Full disclosure: Most of my knowledge about drug development protocols was gained while I worked for a pharmaceutical company for five years in the 1990s. I was a supervisor in a chemical control lab that tested FDA approved prescription drugs. I was not directly involved in research and development or with testing experimental drugs on animals, but both were located at the same company site. Animal rights protests and violence prompted the company to build a high security fence that included parking lots in order to protect employees.
[1.] “In an emailed statement to MedPage Today, NIAID said the contract for “preclinical pharmacology and toxicology services” was conducted “as required in animal models by the FDA, in compliance with Good Laboratory Practice (GLP) guidelines and in a facility accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) or its equivalent.” from https://www.medpagetoday.com/special-reports/exclusives/95275 Oct. 26, 2021
Jim Hoft reports at Gateway Pundit Nebraska AG Issues Opinion on Doctors Prescribing HCQ and Ivermectin for COVID Treatment Will Not Face Punishment. Excerpts in italics with my bolds.
The Office of the Attorney General in Nebraska issued an opinion Friday in response to the request of the Nebraska Department of Health and Human Services that states there’s no “clear and convincingevidence that a physician who first obtains informed consent and then utilizes Ivermectin or hydroxychloroquine for COVID-19 violates the UCA (Nebraska’s Uniform Credential Act).”
Nebraska Attorney General Doug Peterson together with his Solicitor General and Assistant Attorney General issued their opinion in response to a request by Nebraska Department of Health and Human Services CEO, Dannette Smith. She wanted the AG’s office to examine carefully whether doctors could face legal action or be subject to discipline if they prescribed the meds for COVID treatment.
“Allowing physicians to consider…
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For decades Big Pharma co-opted physicians to prescribe their products over those from competitors. The biggest winnings came when a new patent drug had no competition. And of course, when the patents run out, the generics take over the supply. With the Covid pandemonia, a new dynamic arose to protect vaccine profits against anti-viral generic drugs, especially HCQ and Ivermectin. Daniel Horowitz explains at Blaze Media Louisiana AG Jeff Landry warns pharmacies against blocking COVID treatment. Excerpts in italics with my bolds.
“Never have pharmacists been allowed to practice medicine and get between a doctor and his patient,”stated Louisiana Attorney General Jeff Landry in an interview with TheBlaze. “Most certainly not in middle of a pandemic.”
State attorney general might not be the elected position that comes to mind when assessing the pandemic response, but Landry believes that his counterparts in other states have a vital role to play…
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By Paul Homewood h/t Ian Magness This is utterly criminal. And why is the Telegraph’s Health Reporter crticising this nonsense?Doctors Told To Cut Treatment To Tackle Climate Change — NOT A LOT OF PEOPLE KNOW THAT
Ivermectin Safety Profile. By David Archibald. We have all heard the stories of ivermectin saving thousands of souls around the world every day, and countless more from debilitation and disfigurement by the dreaded Covid. 757 more wordsIvermectin Safety Profile — The Wentworth Report
The article below from Epoch Times reveals the problem that inflates Covid-19 case numbers. PCR tests are great diagnostic tests for confirming the source of an illness; PCR is a terrible screening test for non-symtomatic people. You may also read the original article using the link at the end.
World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus gives a press conference at Geneva’s WHO headquarters on Feb. 24, 2020. (Fabrice Coffrini/AFP via Getty Images)PUBLIC HEALTH INFORMATION
WHO Changes CCP Virus Test Criteria in Attempt to Reduce False Positives
BY MEILING LEE January 23, 2021 Updated: January 24, 2021
In updated guidance published on Jan. 20, the WHO said that lab experts and health care practitioners should also consider the patient’s history and epidemiological risk factors alongside the PCR test in diagnosing the CCP (Chinese Communist Party) virus.
The new guidance could result in significantly fewer daily cases.
“Most PCR assays are indicated as an aid for diagnosis, therefore, health care providers must consider any result in combination with timing of sampling, specimen type, assay specifics, clinical observations, patient history, confirmed status of any contacts, and epidemiological information,” the guidance says.
It’s unclear why the health agency waited over a year to release the new directive. The WHO didn’t reply to an inquiry from The Epoch Times.
Scientists and physicians have raised concerns for many months of an over-reliance on and a misuse of the PCR test as a diagnostic tool since it can’t differentiate between a live infectious virus from an inactivated virus fragment that is not infectious.
Additionally, the high cycle threshold values of most PCR tests—at 40 cycles or higher—increases the risk of false positives. A higher threshold value indicates less viral load and that the person is less likely to be infectious, while a person with a lower cycle threshold value has a higher viral load, or is more infectious.
The WHO did not specify what the threshold value cutoff should be for a positive diagnosis, but said to only “determine if [a] manual adjustment of the PCR positivity threshold is recommended by the manufacturer.”
However, it clarified that when the prevalence of the CCP virus is low, “the risk of false positive increases” meaning that “the probability that a person who has a positive result (SARS-CoV-2 detected) is truly infected with SARS-CoV-2 decreases as prevalence decreases, irrespective of the claimed specificity [of the PCR test].”
SARS-CoV-2 is the scientific name for the CCP virus that causes the disease COVID-19.
The Centers for Disease Control and Prevention (CDC) says its PCR tests have a cycle threshold cutoff of 40 cycles. The federal agency finally included information on cycle threshold value in its Frequently Asked Questions about COVID-19 for laboratories on Nov. 12, 2020.
But many medical experts consider a threshold value cutoff of 40 cycles to only return false positives since samples that go through many amplification cycles will pick up negligible RNA sequences regardless if the virus is inactivate or the viral load is exceedingly low to pose any problem.
Prior to the CCP virus pandemic, for individuals to be considered a case, they must test positive and show clinical signs and symptoms. But to be counted as a CCP virus case, only a positive PCR test is required. And no matter how many times an individual is tested, each positive test is counted as a separate case.
The WHO is now advising that a positive PCR test that does “not correspond with the clinical presentation” should be verified by taking “a new specimen” and retesting it.
This advice may also help lower CCP virus cases in hospitals as it more clearly defines who is considered a hospitalized case.
The UK’s National Health Service (NHS) Director of International Relations Dr. Layla McCay confirmed to talkRADIO that a percentage of hospitalized patients officially counted as positive cases were actually being treated for different illnesses not related to COVID-19. They had only tested positive for the disease at the hospital without displaying any symptoms.https://platform.twitter.com/embed/index.html?creatorScreenName=EpochTimes&dnt=false&embedId=twitter-widget-0&frame=false&hideCard=false&hideThread=false&id=1346363750006317056&lang=en&origin=https%3A%2F%2Fwww.theepochtimes.com%2Fwho-changes-ccp-virus-test-criteria-in-attempt-to-reduce-false-positives_3668064.html&siteScreenName=EpochTimes&theme=light&widgetsVersion=ed20a2b%3A1601588405575&width=550px
Dr Layla McCay, NHS Confederation director, confirms to Julia that the hospital figures for “Covid patients” include patients who are not being treated for Covid but have simply tested positive while being treated for something else.@JuliaHB1 | @LaylaMcCay pic.twitter.com/xSud6LW13M
— talkRADIO (@talkRADIO) January 5, 2021
“It is correct that in hospital, people who tested positive for COVID will be the full range of symptoms,” McCay said. “Some will have it as an aside to some other problem for which they’re in the hospital.”
The day after the WHO released its new guidance, Chief Medical Adviser to President Joe Biden, Dr. Anthony Fauci, said the United States would rejoin the organization.
“As such, I am honored to announce that the United States will remain a member of the World Health Organization,” Fauci said. “Yesterday, President Biden signed letters retracting the previous administration’s announcement to withdraw from the organization, and those letters have been transmitted to the secretary-general of the United Nations and to you Dr. Tedros, my dear friend.”
Tedros Adhanom Ghebreyesus is the director-general of the WHO.
“The United States also intends to fulfill its financial obligations to the organizations,” Fauci added.
In July last year, the Trump administration pulled out of the WHO over its alleged role in helping the Chinese communist regime cover up the severity of the CCP virus.
There have been mixed responses from Congress over Biden’s decision to rejoin the WHO.
Rep. Lauren Boebert (R-Colo.) introduced a bill (pdf) on Jan. 21 to “prohibit the availability of United States contributions to the World Health Organization until Congress receives a full report on China and the COVID-19 pandemic, and for other purposes.”
She said in a statement: “The WHO is China-centric and panders to Beijing at every turn. There is no reason U.S. taxpayers should contribute more than $400 million annually to an organization that covered for China and failed to contain the spread of the COVID-19 pandemic.”
Prior to former President Donald Trump withdrawing from the WHO, the United States contributed the most money to the health agency, according to State Department statistics.
My latest in the Washington Times (Web | PDF). A new study claims that air emissions from farms kill 17,000 Americans per year. It’s the first shot in a second try by the Biden administration’s Environmental Protection Agency to control American farms through junk science-fueled air pollution regulations. The study is funded by a $10 […]Biden’s coming war on farmers — JunkScience.com
Click on the link above to view video of Part 2 of Steve Hilton’s investigation into the origins of Covid-19.
Click on the link above to view video of Steve Hilton’s investigation into the origins of the Covid-19 virus.